Slide 76:Now, this a 7 year-old boy who started with me late
1995/early 1996. Again, I want to bring out the timeline here. He had a history of
pneumonia as a child, frequent ear infections, high fever. By the second year of life he
had no real speech, no specific words. This mother said she was worried from the very
beginning. Many of you have come to me and said, my child wasnt quite right
from the beginning. The key is that many children are different. As a pediatrician I
can tell you that within the same family healthy children have different personalities.
But, on the other hand, I believe that some of these children are being hit by a virus
fairly early. What was important here was that the mother had been told by good pediatric
neurologists, good developmental pediatricians, that there was nothing wrong with her
child. Thats part of what youre looking for; that the child does not fit into
a given, known, developmental disorder.
So, when I met him, I got a NeuroSPECT scan. It showed temporal hypoperfusion. We had a
significant finding here of low natural killer cells and, in this case, an interferon
alpha that many researchers will say is unbelievably high above 500. This childs was
1612. That is one of your cytokines, but it is a very clean marker to say that there is a
virus in the background. He also had a borderline HHV6 titer. And interestingly, he had
positive Coxsackie B3 and B4 titers.
Now there is a very interesting story there. In adults with Chronic Fatigue Syndrome,
this country has focused on the idea of herpes-related viruses. And the reason for that is
that we know that herpes viruses can live in your body for a long time and can create some
of these low grade infections. Cold sores are herpes when they reactivate. Vaginal sores
are herpes. And, we have focused on discussions of Epstein-Barr, CMV, HHV6. The British,
interestingly enough, focus on what they call the Coxsackie-Echo viruses, and they see
them causing the same type of herpes-like syndromes in that population. So again, we can
argue; is it going to be a herpes virus, is it going to be a coxsackie virus, is it going
to be a retro-virus? These are areas we need to research. The key is that we need to help
your children now with the knowledge we have while we accelerate the research to define
those specific answers.