Functional Deficits in Autistic Disorder: Characterization by Te-99m-HMPAO - SPECT. J.M.Mountz, C. Tolbert, Duncan W. Lill, et. al. The Journal of Nuclear Medicine. Vol. 36 N0. 7 July 1995
Results - in the autistic patients:
- Abnormally low rCBF values located
predominately in the temporal and parietal lobes
- Left cerebral hemisphere showing greater rCBF
abnormalities than the right
- No difference in rCBF values were found between
the two normal and the five other controls
Abnormal temporal lobe function possibly plays a role in the pathogenesis of autism, since normal functioning of the amygdala and hippocampus is crucial to the regulation and integration of affect, memory and learning.